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A Cl--regulated structural switch that controls proton sensitivity of acid-sensing ion channels

Acid-sensing ion channel (ASIC) has a prominent role in tissue pH-sensing and neuronal signaling, and participates in va......

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acid-sensing ion channel channel gating salt bridge

Unique heteromeric Kir4.1/Kir5.1 channels gating

The gating mechanisms of ion channels are normally revealed by single-channel kinetics analysis through readily monitore......

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Markov models channel gating kinetics Kir4.1/Kir5.1 channel

The Nonproton Ligand Sensing Domain is Required for Paradoxical Stimulation of ASIC3 Channels by Ami

Acid-sensing ion channels (ASICs), which belong to the epithelial sodium channel/degenerin (ENaC/DEG) family, are activa......

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ASIC3 amiloride nonproton ligand sensor channel gating pain

Inter-subunit interaction between Knuckle and Finger domains contributes to proton-induced gating of

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Channel gating Acid-sensing ion channel Inter-subuinit interaction

A non-proton ligand sensor in the acid-sensing ion channel

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Channel gating Acid-sensing ion channel non-proton ligand sensor

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